Difference between revisions of "Enzymes"

From DISI
Jump to navigation Jump to search
m (1 revision)
Line 9: Line 9:
  
 
[[Category:Biology]]
 
[[Category:Biology]]
[[Category:Vocabulary]]
+
[[Category:Docktionary]]

Revision as of 18:21, 21 October 2012

Enzymes generally make excellent targets for small molecule ligand discovery because

  • they are pre-organized to carry out a reaction and thus have destabilizing unsatisfied residues that are available for ligand binding
  • there is often a chemical starting point available in the form of the endogenous ligand
  • there is hope that interfering with catalysis will have an effect because a bound ligand directly competes with the natrual substrate.


Back to targets.