Difference between revisions of "Enzymes"

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Back to [[targets]].
 
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[[Category:Jargon]]
[[Category:Biology]]
 
[[Category:Vocabulary]]
 

Latest revision as of 17:07, 14 February 2014

Enzymes generally make excellent targets for small molecule ligand discovery because

  • they are pre-organized to carry out a reaction and thus have destabilizing unsatisfied residues that are available for ligand binding
  • there is often a chemical starting point available in the form of the endogenous ligand
  • there is hope that interfering with catalysis will have an effect because a bound ligand directly competes with the natrual substrate.


Back to targets.